Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
San Pin Steve Wu, Elvis Quiroz ... Francesco J DeMayo
Genome-wide epigenetic profiling reveals chromatin regions in the human myometrium involved in functional regulation and hormonal control during pregnancy.
A dynamic DNA methylation 'barcode' on the X chromosome can distinguish thousands of individual adult male neurons and may record aspects of their development.
A temporally stable and cell-type-specific genetic driver library provides the means to access and manipulate neuronal lineages in the fly nervous system during development and adulthood.
Daniel de la Fuente, Maria Maroto ... Alfonso Gutierrez-Adan
The oocyte zona pellucida needs to interact with an oviduct protein called OVGP1 to ensure that only sperm from the same species can fertilize the egg.
Hiam Chemaitelly, Houssein H Ayoub ... Laith J Abu-Raddad
A pronounced and consistent healthy vaccinee effect has been identified in rigorously conducted vaccine effectiveness studies, specifically within the first 6 months post-vaccination and among older or clinically vulnerable individuals, likely driven by lower vaccination rates among severely ill populations.
Yevheniia Ishchenko, Amanda T Jeng ... Anthony J Koleske
Heterozygosity for Trio variants leads to overlapping but distinct impacts on behavior, neuronal structure, and synaptic transmission, including newly characterized defects in presynaptic function.
David Duneau, Pierre DM Lafont ... Jean-Baptiste Ferdy
A mathematical model of pathogen within-host dynamics and experimental validations elucidates the interplay between immune response, damage and pathogen proliferation, highlighting the limitations of current experimental proxies and proposing new methods to better understand host resistance and disease tolerance.